He married Anna Constable Owen in 1641 in Jamestown, Va.
He died March 1, 1664, near Dividing Creek, a stream in Northumberland County, Virginia.
According to the website www.anusha.com/pafg568.htm, with an attribution to KHF333@aol.com:
Colonel Richard Henry Lee was born around 1618 and died in 1664. He was a merchant and trader who owned two ships and became a wealthy planter.
He came to America in 1641 as secretary of the king's privy council. In 1642, he received a one-thousand-acre grant called Indian Springs, which he claimed as headright land for transport of his wife Anna. By 1648, he had patented other large tracts of land in York, Gloucester, and upper Norfolk counties.
He served as attorney general of the Virginia colony in 1643, secretary of the colony in 1651, and burgess of York in 1663.
In 1663, Richard Henry Lee returned to England to settle his English estate and arrange for the education of his children. His will is mentioned in Charles Campbell's History of Virginia, page 157. He died in 1664, leaving his wife Anna his plantations Stratford-on-Potownacke and Mock Neck, and another plantation, Paper-Maker's Neck, to his son, Francis.
According to Wikipedia, some 4,400 acres near Dividing Creek, where Richard Henry Lee died in 1664, was assigned by 1655 as a reservation for the Algonquian-speaking Wicocomico and Chickacoan tribes.